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Article

Phenome-wide functional dissection of pleiotropic effects highlights key molecular pathways for human complex traits.

Scientific reports - 23 Jan 2020

Shikov Anton E, Skitchenko Rostislav K, Predeus Alexander V, Barbitoff Yury A

Abstract excerpt

Over the recent decades, genome-wide association studies (GWAS) have dramatically changed the understanding of human genetics. A recent genetic data release by UK Biobank (UKB) has allowed many researchers worldwide to have comprehensive look into the genetic architecture of thousands of human phenotypes. In this study, we used GWAS summary statistics derived from the UKB cohort to investigate functional...

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Identifiers

PMID: 31974475
DOI: 10.1038/s41598-020-58040-4
PMCID: PMC6978431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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