Article
A global overview of genetically interpretable multimorbidities among common diseases in the UK Biobank.
Genome medicine - 5 Jul 2021
Dong Guiying, Feng Jianfeng, Sun Fengzhu, Chen Jingqi, Zhao Xing-Ming
Abstract excerpt
BACKGROUND: Multimorbidities greatly increase the global health burdens, but the landscapes of their genetic risks have not been systematically investigated. METHODS: We used the hospital inpatient data of 385,335 patients in the UK Biobank to investigate the multimorbid relations among 439 common diseases. Post-GWAS analyses were performed to identify multimorbidity shared genetic risks at the genomic loci,...
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