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Using Machine Learning to identify microRNA biomarkers for predisposition to Huntington’s Disease

2022-08-16

Abstract excerpt

<h4>Background</h4> Huntington’s disease (HD) is an autosomal dominant disease which is triggered by a large expansion of CAG nucleotides in the HTT gene. While the CAG expansion linearly correlates with the age of disease onset in HD, twin-studies and cohorts of Juvenile Onset HD (JOHD) patients have shown other factors influence the progression of HD. Thus, it would be of interest to identify molecular biomark...

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Literature Corpus work
d99a8030-2e32-5610-8507-8b2dc6eb804c
DOI
10.1101/2022.08.16.504104
Open publication

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Using Machine Learning to identify microRNA biomarkers for predisposition to Huntington’s DiseaseDOI 10.1101/2022.08.16.504104
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