Article

Abnormal molecular signatures of inflammation, energy metabolism and vesicle biology in human Huntington disease peripheral tissues

2022-02-06

Abstract excerpt

<h4>Background</h4> A major challenge in neurodegenerative diseases concerns identifying biological disease signatures that track with disease progression or respond to an intervention. Several clinical trials in Huntington disease (HD), an inherited, progressive neurodegenerative disease, are currently ongoing. Therefore, we examined whether peripheral tissues can serve as a source of readily accessible biologic...

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Literature Corpus work: c0ecb09b-4310-513a-b1f6-37579ef0bea6
DOI: 10.1101/2022.02.03.475821

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