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Article

What, When and How to Measure-Peripheral Biomarkers in Therapy of Huntington's Disease.

International journal of molecular sciences - 4 Feb 2021

Przybyl Lukasz, Wozna-Wysocka Magdalena, Kozlowska Emilia, Fiszer Agnieszka

Abstract excerpt

Among the main challenges in further advancing therapeutic strategies for Huntington's disease (HD) is the development of biomarkers which must be applied to assess the efficiency of the treatment. HD is a dreadful neurodegenerative disorder which has its source of pathogenesis in the central nervous system (CNS) but is reflected by symptoms in the periphery. Visible symptoms include motor deficits and slight...

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Identifiers

PMID: 33557131
DOI: 10.3390/ijms22041561
PMCID: PMC7913877

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