Article

Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells

2022-06-27

Abstract excerpt

<h4>SUMMARY</h4> Spinal motor neurons deficiency results in a series of devastating disorders such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA) and spinal cord injury (SCI). These disorders are currently incurable, while human pluripotent stem cells (hPSCs)-derived spinal motor neurons are promising but suffered from low-efficiency, functional immaturity and lacks of posterior cellular id...

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Literature Corpus work: 556fbb62-e165-5aca-a40a-30bfa29cf40d
DOI: 10.1101/2022.06.26.495599

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