Article

Species-specific progenitor sub-domain extends neurogenesis and increases human motor neuron production

2023-06-22

Abstract excerpt

<title>Abstract</title> <p>Neurogenesis lasts ~10 times longer in developing humans compared to mice, resulting in a >1000-fold increase in the number of neurons in the central nervous system (CNS). To identify molecular and cellular mechanisms contributing to this difference, we studied human and mouse motor neurogenesis using a stem cell differentiation system that recapitulates species-specific scales of devel...

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Literature Corpus work: 97146b9c-a855-5721-af4e-da7f7865c81a
DOI: 10.21203/rs.3.rs-2855830/v1

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