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Article

TULIPs: tunable, light-controlled interacting protein tags for cell biology.

Nature methods - 4 Mar 2012

Strickland Devin, Lin Yuan, Wagner Elizabeth, Hope C Matthew, Zayner Josiah, Antoniou Chloe, Sosnick Tobin R, Weiss Eric L, Glotzer Michael

Abstract excerpt

Naturally photoswitchable proteins offer a means of directly manipulating the formation of protein complexes that drive a diversity of cellular processes. We developed tunable light-inducible dimerization tags (TULIPs) based on a synthetic interaction between the LOV2 domain of Avena sativa phototropin 1 (AsLOV2) and an engineered PDZ domain (ePDZ). TULIPs can recruit proteins to diverse structures in living...

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Identifiers

PMID: 22388287
DOI: 10.1038/nmeth.1904
PMCID: PMC3444151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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