Article
iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wildtype cells
2023-05-10
Abstract excerpt
To understand gene function, it is necessary to compare cells carrying the mutated target gene with normal cells. In most biomedical studies, the cells being compared are in different mutant and control animals and therefore do not experience the same epigenetic changes and tissue microenvironment. The experimental induction of genetic mosaics is essential to determine a gene cell-autonomous function and to model...
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Identifiers and source
- Literature Corpus work
- 44268825-097e-58ab-aec3-c656572a3b38
- DOI
- 10.1101/2023.05.09.540000
