Article

Molecular Characterization of 11q Deletions Points to a Pathogenic Role of the ATM Gene in Mantle Cell Lymphoma

1999-11-01

Abstract excerpt

Abstract Deletions involving the long arm of chromosome 11 (11q) have been recently found as recurrent chromosome aberrations in mantle cell lymphoma (MCL). In the current study, the incidence and molecular extent of 11q deletions were analyzed in a series of 81 MCL by fluorescence in situ hybridization with probes from a contiguous set of yeast artificial chromosomes (YACs). Loss of chromosome 11 material was obs...

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Literature Corpus work: d9391165-6b6f-50d6-a376-399c5656ab6f
DOI: 10.1182/blood.v94.9.3262

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