Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome.

Blood - 1 Jun 2005

Rubio-Moscardo Fanny, Climent Joan, Siebert Reiner, Piris Miguel A, Martín-Subero Jose I, Nieländer Inga, Garcia-Conde Javier, Dyer Martin J S, Terol Maria Jose, Pinkel Daniel, Martinez-Climent Jose A

Abstract excerpt

To identify recurrent genomic changes in mantle cell lymphoma (MCL), we used high-resolution comparative genomic hybridization (CGH) to bacterial artificial chromosome (BAC) microarrays in 68 patients and 9 MCL-derived cell lines. Array CGH defined an MCL genomic signature distinct from other B-cell lymphomas, including deletions of 1p21 and 11q22.3-ATM gene with coincident 10p12-BMI1 gene amplification and 10p14...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Artificial, Bacterial
Share to Genomics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Leukemia

Share to Lymphoma, Mantle-Cell

Share to Oligonucleotide Array Sequence Analysis

Share to Sequence Deletion

Share to Survival Rate

Share to Treatment Outcome

Source

Identifiers

PMID: 15718413
DOI: 10.1182/blood-2004-10-3907

Genes

ATM
BMI1
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome.PMID 15718413Read ↗

Novel chromosomal imbalances in mantle cell lymphoma detected by genome-wide array-based comparative genomic hybridizationSemantic proximity Read ↗

Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomesSemantic proximity Read ↗

Allelic genotyping reveals a hierarchy of genomic alterations in mantle cell lymphoma associated to cell proliferation.Semantic proximity Read ↗

Surveying the Genomic Landscape of Mantle Cell Lymphoma Indicates the Importance of Multimodal Genomic and Transcriptomic ExplorationSemantic proximity Read ↗

Increased number of chromosomal imbalances and high-level DNA amplifications in mantle cell lymphoma are associated with blastoid variants.Semantic proximity Read ↗

Comparative genome profiling across subtypes of low-grade B-cell lymphoma identifies type-specific and common aberrations that target genes with a role in B-cell neoplasiaSemantic proximity Read ↗

Detailed assessment of copy number alterations revealing homozygous deletions in 1p and 13q in mantle cell lymphoma.Semantic proximity Read ↗

Comparison of genome profiles for identification of distinct subgroups of diffuse large B-cell lymphomaSemantic proximity Read ↗

Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling.Semantic proximity Read ↗

Functional genomics and tumor microenvironment analysis reveal prognostic biological subtypes in Mantle cell lymphoma.Semantic proximity Read ↗

Array comparative genomic hybridization reveals genomic copy number changes associated with outcome in diffuse large B-cell lymphomasSemantic proximity Read ↗

Array comparative genomic hybridization identifies genetic regions associated with outcome in aggressive diffuse large B‐cell lymphomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.