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Proteomic signatures of cognitive resilience in LOU/c/Jall rats converge with inverse hippocampal axes of Alzheimer’s disease

2026-07-05

Abstract excerpt

<h4>ABSTRACT</h4> Why some individuals maintain good level of cognitive performances during aging, others don’t or even progress toward Alzheimer’s disease. We profiled the hippocampal proteome of adult LOU/c/Jall rats, a strain associated with spontaneous cognitive longevity, and compared this proteomic state with a published human hippocampal Alzheimer’s disease dataset. Because individual protein changes did n...

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Literature Corpus work
d9377f19-6c5f-5b2f-819a-d4f8a2e3a496
DOI
10.64898/2026.06.30.735140
Open publication

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Proteomic signatures of cognitive resilience in LOU/c/Jall rats converge with inverse hippocampal axes of Alzheimer’s diseaseDOI 10.64898/2026.06.30.735140
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