Article

Discovery of allele-specific protein-RNA interactions in human transcriptomes

2018-08-10

Abstract excerpt

Gene expression is tightly regulated at the post-transcriptional level through splicing, transport, translation, and decay. RNA-binding proteins (RBPs) play key roles in post-transcriptional gene regulation, and genetic variants that alter RBP-RNA interactions can affect gene products and functions. We developed a computational method ASPRIN (Allele-Specific Protein-RNA Interaction), that uses a joint analysis of...

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Literature Corpus work: d90ce718-cdfb-5f0d-9014-3ad79cd45c61
DOI: 10.1101/389205

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