Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide mapping of allele-specific protein-DNA interactions in human cells.

Nature methods - 1 Apr 2008

Maynard Nathaniel D, Chen Jing, Stuart Rhona K, Fan Jian-Bing, Ren Bing

Abstract excerpt

We describe a high-throughput method, named ChIP-SNP, for the identification of allele-specific protein-DNA interactions throughout the human genome. ChIP-SNP combines chromatin immunoprecipitation (ChIP) with whole-genome single nucleotide polymorphism (SNP) genotyping microarray analysis. We demonstrated that it can be used to accurately identify allele-specific binding of RNA polymerase II (RNAP) in the human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to Chromosome Mapping
Share to Fibroblasts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression

Share to Genome, Human

Share to Genomic Imprinting

Share to Protein Binding

Share to RNA Polymerase II

Source

Identifiers

PMID: 18345007
DOI: 10.1038/nmeth.1194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide mapping of allele-specific protein-DNA interactions in human cells.PMID 18345007Read ↗

Genome-wide allele-specific analysis: insights into regulatory variation.Semantic proximity Read ↗

Discovery of allele-specific protein-RNA interactions in human transcriptomesSemantic proximity Read ↗

Simultaneous SNP identification and assessment of allele-specific bias from ChIP-seq data.Semantic proximity Read ↗

Interrogation of allelic chromatin states in human cells by high-density ChIP-genotyping.Semantic proximity Read ↗

Landscape of allele-specific transcription factor binding in the human genomeSemantic proximity Read ↗

Landscape of allele-specific transcription factor binding in the human genome.Semantic proximity Read ↗

A uniform survey of allele-specific binding and expression over 1000-Genomes-Project individuals.Semantic proximity Read ↗

Allele-specific DNA methylation: beyond imprinting.Semantic proximity Read ↗

SNP-based large-scale identification of allele-specific gene expression in human B cells.Semantic proximity Read ↗

Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human.Semantic proximity Read ↗

Allele-specific binding of RNA-binding proteins reveals functional genetic variants in the RNASemantic proximity Read ↗

A genome-wide interactome of DNA-associated proteins in the human liver.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.