Article

Long-read RNA-seq demarcates <i>cis</i> - and <i>trans</i> -directed alternative RNA splicing

2024-06-14

Abstract excerpt

Genetic regulation of alternative splicing constitutes an important link between genetic variation and disease. Nonetheless, RNA splicing is regulated by both cis -acting elements and trans -acting splicing factors. Determining splicing events that are directed primarily by the cis - or trans -acting mechanisms will greatly inform our understanding of the genetic basis of disease. Here, we show that long-read...

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Literature Corpus work: 59a6312e-fb4d-58b7-a83b-fbe602f869ad
DOI: 10.1101/2024.06.14.599101

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