Article
Altered Gene Expression Associated with microRNA Binding Site Polymorphisms.
PloS one - 1 Jan 2015
Võsa Urmo, Esko Tõnu, Kasela Silva, Annilo Tarmo
Abstract excerpt
Allele-specific gene expression associated with genetic variation in regulatory regions can play an important role in the development of complex traits. We hypothesized that polymorphisms in microRNA (miRNA) response elements (MRE-SNPs) that either disrupt a miRNA binding site or create a new miRNA binding site can affect the allele-specific expression of target genes. By integrating public expression...
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