Article

Gene Regulatory Network Inference as Relaxed Graph Matching

2020-06-24

Abstract excerpt

Gene regulatory network inference is instrumental to the discovery of genetic mechanisms driving diverse diseases, including cancer. Here, we present a theoretical framework for PANDA, an established method for gene regulatory network inference. PANDA is based on iterative message passing updates that resemble the gradient descent of an optimization problem, OTTER, which can be interpreted as relaxed inexact graph...

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Identifiers and source

Literature Corpus work: a161fb17-df27-5bea-bab6-ae282e1c728f
DOI: 10.1101/2020.06.23.167999

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