A prior-based integrative framework for functional transcriptional regulatory network inference.

Abstract excerpt

Transcriptional regulatory networks specify regulatory proteins controlling the context-specific expression levels of genes. Inference of genome-wide regulatory networks is central to understanding gene regulation, but remains an open challenge. Expression-based network inference is among the most popular methods to infer regulatory networks, however, networks inferred from such methods have low overlap with...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Gene Expression
• Share to Gene Regulatory Networks