Article

scGRIP: a graph-based explainable AI framework for single-cell multi-omics Gene Regulatory Inference with Prior Knowledge

2025-01-27

Abstract excerpt

Multi-omics sequencing technologies can jointly measure transcriptome and chromatin accessibility at the single-cell resolution. This enables inference of gene regulatory networks (GRNs) at the cellular level, thereby elucidating high-resolution differential GRNs associated with diseases. However, existing methods lack interpretability and scalability. We present single-cell Gene Regulatory Inference with Prior kn...

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Literature Corpus work: 2c1e5cdf-847f-5f92-ab0b-47dc57f81f74
DOI: 10.1101/2025.01.24.634773

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