Article

A rapid, facile, and economical method for the isolation of ribosomes and translational machinery for structural and functional studies

2024-10-22

Abstract excerpt

<h4>Short abstract</h4> Ribosomes are essential RNA-protein complexes involved in protein synthesis and quality control. Traditional methods for ribosome isolation are labor intensive, expensive, and require substantial biological material. In contrast, our new method, RAPPL (RNA Affinity Purification using Poly-Lysine), offers a rapid, simple, and cost-effective alternative. This method enriches ribosomes and as...

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Literature Corpus work: d8cf7c27-c772-508d-941f-d47832b5c964
DOI: 10.1101/2024.10.21.619433

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