Article
Finding priority ribosomes for future structural and pathogen research based upon global RNA and protein sequence analysis
2021-06-14
Abstract excerpt
Ribosome-targeting antibiotics comprise over half of antibiotics used in medicine, but our fundamental knowledge of their binding sites is derived primarily from ribosome structures from non-pathogenic species. These include Thermus thermophilus, Deinococcus radiodurans and Haloarcula marismortui , as well as commensal and pathogenic Escherichia coli . Advancements in electron cryomicroscopy have allowed for th...
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Identifiers and source
- Literature Corpus work
- fd0750c3-f919-5cea-801b-0a690a120d52
- DOI
- 10.1101/2021.06.14.448437
