Article

Patient-Derived Organoids Recapitulate Intrinsic Immune Landscapes and Progenitor Populations of Glioblastoma

2021-10-09

Abstract excerpt

<h4>Summary</h4> Glioblastoma stem cells (GSCs) are highly self-renewing, resistant to therapy, and are able to form lethal tumors 1, 2 . Tumor organoids have been developed to study tumor evolution 1–4 , and while GSCs can form organoids for glioblastoma multiforme, our understanding of their intrinsic immune, metabolic, genetic, and molecular programs is limited. To address this, we deeply characterized GSC-d...

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Literature Corpus work: 5b1ad614-3a85-5bb2-a8d1-fd32cad442b7
DOI: 10.1101/2021.10.06.463228

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