Article

Conserved structural features of the lncRNA HOTAIR in breast cancer cells

2026-05-20

Abstract excerpt

<h4>ABSTRACT</h4> Long noncoding RNAs (lncRNAs) regulate diverse cellular processes and are frequently implicated in disease, but their functional mechanisms often remain elusive. One such lncRNA, HOTAIR (Hox transcript antisense intergenic RNA), is a ∼2.1 kb mammalian transcript whose overexpression promotes invasion and metastasis in breast cancer. However, the mechanisms by which HOTAIR influences gene regulat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d8a316e9-abd4-5bf9-9a0f-ed97e117b0c2
DOI: 10.64898/2026.05.18.725451

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Conserved structural features of the lncRNA HOTAIR in breast cancer cellsDOI 10.64898/2026.05.18.725451Read

Molecular anatomy and plasticity of the long noncoding RNA HOTAIRSemantic proximity Read

Long-Noncoding-RNA HOTAIR Upregulation is Associated with Poor Breast Cancer Outcome: A Systematic Review and Meta AnalysisSemantic proximity Read

HOTAIR ancient sequence suggests regulatory roles both in cis and transSemantic proximity Read

A single N6-methyladenosine site in lncRNA HOTAIR regulates its function in breast cancer cellsSemantic proximity Read

Inducible lncRNA transgenic mice reveal continual role of HOTAIR in promoting breast cancer metastasisSemantic proximity Read

Orthogonal Proteomics Methods to Unravel the HOTAIR InteractomeSemantic proximity Read

LncRNA HOTAIR Polymorphisms Association with Cancer Susceptibility in Different Tumor Types.Semantic proximity Read

Quantitative Assessment of the Polymorphisms in the HOTAIR lncRNA and Cancer Risk: A Meta-Analysis of 8 Case-Control Studies.Semantic proximity Read

Conserved architecture of a functional lncRNA-protein interaction in the DNA damage response pathwaySemantic proximity Read

A novel histone H4 variant regulates rDNA transcription in breast cancerSemantic proximity Read

Incorporating histone H2B variants into chromatin modifies chromatin accessibility to induce epithelial-to-mesenchymal transition in breast cancerSemantic proximity Read

Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancerSemantic proximity Read