Article

Incorporating histone H2B variants into chromatin modifies chromatin accessibility to induce epithelial-to-mesenchymal transition in breast cancer

2024-12-21

Abstract excerpt

Histones scaffold genomic DNA and regulate access to the transcriptional machinery. However, naturally occurring histone variants can alter histone-DNA interactions, DNA and histone modifications, and the chromatin interactome. Hence, alterations in histone variant deposition can disrupt chromatin, and are increasingly recognized as a way to trigger various disease, including cancer. While significant attention ha...

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Literature Corpus work: e6c8a37c-9f58-5bf6-9c39-741dd2202b24
DOI: 10.1101/2024.12.21.627414

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Incorporating histone H2B variants into chromatin modifies chromatin accessibility to induce epithelial-to-mesenchymal transition in breast cancerDOI 10.1101/2024.12.21.627414Read

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