Article
Quantitative Assessment of the Polymorphisms in the HOTAIR lncRNA and Cancer Risk: A Meta-Analysis of 8 Case-Control Studies.
PloS one - 1 Jan 2016
Tian Tian, Li Chunjian, Xiao Jing, Shen Yi, Lu Yihua, Jiang Liying, Zhuang Xun, Chu Minjie
Abstract excerpt
HOX transcript antisense intergenic RNA (HOTAIR) is a long non-coding RNA (lncRNA) that functions as an oncogenic molecule in different cancer cells. Genetic variants of HOTAIR may affect the activity of certain regulatory factors and further regulate the aberrant expression of HOTAIR, which might be underlying mechanisms that affect tumour susceptibility and prognosis. Recently, several studies have been...
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