Article

HOTAIR ancient sequence suggests regulatory roles both in cis and trans

2018-01-22

Abstract excerpt

<h4>ABSTRACT</h4> HOTAIR is a long noncoding RNA transcribed between HOXC11 and HOXC12 in mammals. The proposed function(s) of HOTAIR lacks consensus as to whether it regulates HoxD cluster genes in trans or HoxC cluster genes in cis . We have identified a 32-nucleotide long conserved noncoding element (CNE) as HOTAIR ancient sequence which has a paralogous copy embedded in HOXD11 noncoding transcript. All...

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Literature Corpus work: 56fdaf60-7c2b-52e0-a3af-0a565cca8f38
DOI: 10.1101/250621

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