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Article

LncRNA HOTAIR Polymorphisms Association with Cancer Susceptibility in Different Tumor Types.

Current drug targets - 1 Jan 2018

Botti Gerardo, Collina Francesca, Scognamiglio Giosuè, Aquino Gabriella, Cerrone Margherita, Liguori Giuseppina, Gigantino Vincenzo, Malzone Maria Gabriella, Cantile Monica

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in non-coding RNAs (ncRNA) molecules affect gene and protein expression and generate genetic variability influencing the risk of tumor diseases. HOTAIR locates at the heart of the cell memory gene program and represents a prototype of long non coding RNA (LncRNA) due to its capacity to regulate in-trans a distant chromosome landscape. Aberrant expression of HOTAIR is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28641521
DOI: 10.2174/1389450118666170622091940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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