Article

Roles for Mitochondrial Complex I subunits in regulating synaptic transmission and growth

2022-01-01

Abstract excerpt

To identify conserved components of synapse function that are also associated with human diseases, we conducted a genetic screen. We used the Drosophila melanogaster neuromuscular junction (NMJ) as a model. We employed RNA interference (RNAi) on selected targets and assayed synapse function and plasticity by electrophysiology. We focused our screen on genetic factors known to be conserved from human neurological...

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Literature Corpus work: d84dc038-cd7a-5a25-aac2-3e87fb15bf20
DOI: 10.1101/2021.12.30.474605

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