Article

Mitochondrial Complex I and ROS control neuromuscular function through opposing pre- and postsynaptic mechanisms

2024-12-31

Abstract excerpt

<h4>ABSTRACT</h4> Neurons require high amounts energy, and mitochondria help to fulfill this requirement. Dysfunctional mitochondria trigger problems in various neuronal tasks. Using the Drosophila neuromuscular junction (NMJ) as a model synapse, we previously reported that Mitochondrial Complex I (MCI) subunits were required for maintaining NMJ function and growth. Here we report tissue-specific adaptations at...

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Literature Corpus work: 2cc2821e-cef4-54a6-9247-99a652694e0b
DOI: 10.1101/2024.12.30.630694

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