Article
Early Modulation of the Gut Microbiome by Female Sex Hormones Alters Amyloid Pathology and Microglial Function
2023-10-27
Abstract excerpt
It is well-established that women are disproportionately affected by Alzheimer’s disease (AD). The mechanisms underlying this sex-specific disparity are not fully understood, but several factors that are often associated-including interactions of sex hormones, genetic factors, and the gut microbiome-likely contribute to the disease's etiology. Here, we have examined the role of sex hormones and the gut microbiome...
Topics
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- Alzheimer's disease research and treatments
- Dementia and Cognitive Impairment Research
- Dermatology and Skin Diseases
- Drug Transport and Resistance Mechanisms
- Gut microbiota and health
- Maternal Mental Health During Pregnancy and Postpartum
- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
Identifiers and source
- Literature Corpus work
- d84d435f-2e1a-5905-859a-545e6c53e7d4
- DOI
- 10.21203/rs.3.rs-3462284/v1
