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Sex-dependent effects of maternal high-fat diet during lactation in adult THY-Tau22 mice offspring

2025-06-15

Abstract excerpt

The perinatal environment has been suggested to participate to the development of tauopathies and Alzheimer’s disease but the molecular and cellular mechanisms involved remain contradictory and under-investigated. Here, we evaluated the effects of a maternal high-fat diet (HFD) during lactation on the development of tauopathy in the THY-Tau22 mouse strain, a model of progressive tau pathology associated with cogni...

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Literature Corpus work
94dcad0f-24fc-5eb8-be41-963137a74776
DOI
10.1101/2025.06.10.658847
Open publication

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Sex-dependent effects of maternal high-fat diet during lactation in adult THY-Tau22 mice offspringDOI 10.1101/2025.06.10.658847
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