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Activating AMPK-p53 Axis Induced by Mitochondrial Impairment: A Novel Anti-Liver Cancer Mechanism of Sulfane Sulfur

2024-08-02

Abstract excerpt

<title>Abstract</title> <p>Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer and remains refractory to conventional chemotherapy. Sulfane sulfur-based compounds have a long history in the treatment of HCC, but their efficacy has been disappointing. We recently reported a sulfane sulfur donor PSCP, which exhibits improved chemical stability and allows for greater structural modificatio...

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Literature Corpus work
d802debc-522d-5ef7-b32e-f7b78ca6413a
DOI
10.21203/rs.3.rs-4668889/v1
Open publication

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Activating AMPK-p53 Axis Induced by Mitochondrial Impairment: A Novel Anti-Liver Cancer Mechanism of Sulfane SulfurDOI 10.21203/rs.3.rs-4668889/v1
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