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Article

Role of p53 suppression in the pathogenesis of hepatocellular carcinoma

1 Jun 2023

Abstract excerpt

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in the world.Metabolic reprogramming is considered a new hallmark of cancer, but it remains unclearly described in HCC.The dysregulation of the PI3K/AKT/mTOR signaling pathway is common in HCC and is, therefore, a topic of further research and the concern of developing a novel target for liver cancer therapy.In this review, we...

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PMID: 37304923
DOI: 10.4291/wjgp.v14.i3.46

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