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SIRT1 activation promotes energy homeostasis and reprograms liver cancer metabolism

2023-07-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Cancer cells are characterized by uncontrolled cell proliferation and impaired bioenergetics. Sirtuins are a family of highly conserved enzymes that play a fundamental role in energy metabolism regulation. SIRT1, in particular, drives many physiological stress responses and metabolic pathways following nutrient deprivation. We previously showed that SIRT1 activat...

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Literature Corpus work
ff5ee8b9-7a96-56a5-9508-83b272fab836
DOI
10.21203/rs.3.rs-3023425/v1
Open publication

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SIRT1 activation promotes energy homeostasis and reprograms liver cancer metabolismDOI 10.21203/rs.3.rs-3023425/v1
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