Article

Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin

2023-03-05

Abstract excerpt

Multidrug-resistant bacterial pathogens like vancomycin-resistant Enterococcus faecium (VREfm) are a critical threat to human health. Daptomycin is a last-resort antibiotic for VREfm infections with a novel mode-of-action, but for which resistance has surprisingly been widely reported but unexplained. Here we show that rifaximin, an unrelated antibiotic used prophylactically to prevent hepatic encephalopathy in li...

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Literature Corpus work: d8002544-3a67-5688-9534-7f24c3fdeb85
DOI: 10.1101/2023.03.01.23286614

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