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Article

Apramycin efficacy in the treatment of carbapenem-resistant <i>Enterobacterales</i> in murine blood stream infection models

2023-12-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The aminoglycoside apramycin has been proposed as a drug candidate for the treatment of critical Gram-negative systemic infections. However, its potential in the treatment of drug-resistant bloodstream infections (BSIs) has yet to be assessed. <h4>Methods</h4> The resistance gene annotations of 26 493 blood culture isolates were analyzed. In vitro profiling of apramycin co...

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Literature Corpus work
7dcada5a-f104-5f45-b39b-2c9618975318
DOI
10.1101/2023.12.10.570991
Open publication

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Apramycin efficacy in the treatment of carbapenem-resistant <i>Enterobacterales</i> in murine blood stream infection modelsDOI 10.1101/2023.12.10.570991
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