Article
Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides.
Nature microbiology - 1 Jun 2018
Lázár Viktória, Martins Ana, Spohn Réka, Daruka Lejla, Grézal Gábor, Fekete Gergely, Számel Mónika, Jangir Pramod K, Kintses Bálint, Csörgő Bálint, Nyerges Ákos, Györkei Ádám, Kincses András, Dér András, Walter Fruzsina R, Deli Mária A, Urbán Edit, Hegedűs Zsófia, Olajos Gábor, Méhi Orsolya, Bálint Balázs, Nagy István, Martinek Tamás A, Papp Balázs, Pál Csaba
Abstract excerpt
Antimicrobial peptides are promising alternative antimicrobial agents. However, little is known about whether resistance to small-molecule antibiotics leads to cross-resistance (decreased sensitivity) or collateral sensitivity (increased sensitivity) to antimicrobial peptides. We systematically addressed this question by studying the susceptibilities of a comprehensive set of 60 antibiotic-resistant Escherichia...
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