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Allele-Specific Effects of Mutations in the Rifampin Resistance-Determining Region (RRDR) of RpoB on Physiology and Antibiotic Resistance in <i>Enterococcus faecium</i>

2025-08-04

Abstract excerpt

Enterococcus faecium is a member of the human gut microbiota that has evolved into a problematic nosocomial pathogen and leading cause of infections in hospitalized patients. Treatment of E. faecium infections is complicated by antibiotic resistance, making it important to understand resistance mechanisms and their broader consequences in this pathogen. Here we explored the collateral effects of rifampin resistan...

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Literature Corpus work
c3358970-2e51-5450-93f9-4a786b316152
DOI
10.1101/2025.07.25.666922
Open publication

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Allele-Specific Effects of Mutations in the Rifampin Resistance-Determining Region (RRDR) of RpoB on Physiology and Antibiotic Resistance in <i>Enterococcus faecium</i>DOI 10.1101/2025.07.25.666922
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