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Polygenic Risk Scores for Breast Cancer: Modern Approaches to Risk Prediction and Subtype Identification.

Archives of medical research - 1 Apr 2026

Dipp-Martin Krishna, Santuario-Facio Sandra Karina, Ortiz-Lopez Rocío, Argüello-Astorga Rafael, González-Galarza Faviel Francisco

Abstract excerpt

Breast cancer (BC), a complex disease characterized by the uncontrolled proliferation of breast cells, poses a major global health challenge. Its increasing prevalence is influenced by a combination of genetic, environmental, and lifestyle factors. While hereditary mutations in high-risk genes contribute to only a small percentage of cases, the majority may be influenced by common genetic variations that...

Topics

Humans
Breast Neoplasms
Female
Multifactorial Inheritance
Genetic Predisposition to Disease
Risk Assessment
Risk Factors
Precision Medicine
Genetic Risk Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40972140
DOI: 10.1016/j.arcmed.2025.103319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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