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Article

Procarbazine-induced Genomic Toxicity in Hodgkin Lymphoma Survivors

2024-06-05

Abstract excerpt

<h4>Background</h4> Procarbazine-containing chemotherapy regimens associate with cytopenias and infertility, suggesting stem cell toxicity. Procarbazine in eBEACOPP (escalated dose bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisolone) is increasingly replaced with dacarbazine (eBEACOPDac) to reduce toxicity, although limited genomic and clinical data support this substitutio...

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Identifiers and source

Literature Corpus work
d7d55384-98ea-51d8-b19f-7505d368fc00
DOI
10.1101/2024.06.04.24308149
Open publication

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Procarbazine-induced Genomic Toxicity in Hodgkin Lymphoma SurvivorsDOI 10.1101/2024.06.04.24308149
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