Article
The long-term effects of chemotherapy on normal blood cells
2024-05-21
Abstract excerpt
In developed countries, ∼10% of individuals are exposed to systemic chemotherapy for cancer and other diseases. Many chemotherapeutic agents act by increasing DNA damage in cancer cells, triggering cell death. However, there is limited understanding of the extent and long-term consequences of collateral DNA damage to normal tissues. To investigate the impact of chemotherapy on mutation burdens and cell population...
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Identifiers and source
- Literature Corpus work
- 3a88f66f-b854-5d21-8f3f-62d90e1cc171
- DOI
- 10.1101/2024.05.20.594942