Article

Murine <i>Surf4</i> is essential for early embryonic development

2019-02-07

Abstract excerpt

<h4>ABSTRACT</h4> Newly synthesized proteins co-translationally inserted into the endoplasmic reticulum (ER) lumen may be recruited into anterograde transport vesicles by their association with specific cargo receptors. We recently identified a role for the cargo receptor SURF4 in facilitating the secretion of PCSK9 in cultured cells. To examine the function of SURF4 in vivo , we used CRISPR/Cas9-mediated gene e...

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Literature Corpus work: d79e8904-dbe5-5428-814f-02b1d97b2eed
DOI: 10.1101/541995

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