Article

Engineering an <i>fgfr4</i> knockout zebrafish to study its role in development and disease

2024-05-09

Abstract excerpt

Fibroblast growth factor receptor 4 (FGFR4) has a role in many biological processes, including lipid metabolism, tissue repair, and vertebrate development. In recent years, FGFR4 overexpression and activating mutations have been associated with numerous adult and pediatric cancers. As such, FGFR4 presents an opportunity for therapeutic targeting which is being pursued in clinical trials. To understand the role of...

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Literature Corpus work: 2d4a1d4b-0c9b-5177-bb6f-b3b8f4a36347
DOI: 10.1101/2024.05.08.593184

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