Article

Surf4 deficiency reduces intestinal lipid absorption and secretion and decreases metabolism in mice

2023-02-08

Abstract excerpt

<h4>Background</h4> Postprandial dyslipidemia is a causative risk factor for cardiovascular disease. The majority of absorbed dietary lipids are packaged into chylomicron and then delivered to circulation. Previous studies showed that Surfeit4 (Surf4) mediates very low-density lipoprotein secretion from hepatocytes. Silencing hepatic Surf4 markedly reduces the development of atherosclerosis in different mouse mod...

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Literature Corpus work: c13aea24-4ad6-5e3f-9ead-d68a39fba2db
DOI: 10.1101/2023.02.08.527677

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