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MethylBERT:‬ ‭A‬ ‭Transformer-based‬ ‭model‬ ‭for‬ ‭read-level‬ ‭DNA‬ ‭methylation‬ pattern‬ ‭identification‬ ‭and‬ ‭tumour‬ ‭deconvolution‬

2024-05-17

Abstract excerpt

<title>Abstract</title> <p>DNA methylation (DNAm) is a key epigenetic mark that shows profound alterations in cancer. Read-level methylomes enable more in-depth DNAm analysis due to the broad coverage and preservation of rare cell-type signals, compared to array-based data such as 450K/EPIC array. Here, we propose MethylBERT, a novel Transformer-based model for read-level methylation pattern classification. Methy...

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Literature Corpus work
d75bd14c-89d5-5f5d-a80e-8cc35529edbf
DOI
10.21203/rs.3.rs-3915137/v1
Open publication

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MethylBERT:‬ ‭A‬ ‭Transformer-based‬ ‭model‬ ‭for‬ ‭read-level‬ ‭DNA‬ ‭methylation‬ pattern‬ ‭identification‬ ‭and‬ ‭tumour‬ ‭deconvolution‬DOI 10.21203/rs.3.rs-3915137/v1
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