Article

Fatty acid metabolism constrains Th9 cell differentiation and anti-tumor immunity via modulation of retinoic acid receptor signaling

2024-01-17

Abstract excerpt

<title>Abstract</title> T helper 9 cells (Th9) are interleukin 9 (IL-9)–producing cells that have diverse functions ranging from anti-tumor immune responses to driving allergic inflammation. Th9 cells differentiate from naïve CD4+ T cells in the presence of IL-4 and transforming growth factor-beta (TGF-β); however, our understanding of the molecular basis of their differentiation remains incomplete....

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Literature Corpus work: d7444467-703f-58f9-80e6-5d5aab8f99d8
DOI: 10.21203/rs.3.rs-3839261/v1

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