Article

Combinatorial library of biodegradable polyesters enables delivery of plasmid DNA to polarized human RPE monolayers for retinal gene therapy

2018-02-13

Abstract excerpt

<h4>Abstract:</h4> Efficient gene delivery into hard-to-transfect cells is still a challenge despite significant progress in the development of various gene delivery tools. Non-viral and synthetic polymeric nanoparticles offer an array of advantages for gene delivery over the viral vectors and high in demand as they are safe to use, easy to synthesize and highly cell-type specific. Here we demonstrate the use of...

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Literature Corpus work: d73456a8-9c29-5e53-bc18-a90df04c7a4a
DOI: 10.1101/264390

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