Article
Effective gene delivery into human stem cells with a cell-targeting Peptide-modified bioreducible polymer.
Small (Weinheim an der Bergstrasse, Germany) - 6 May 2015
Beloor Jagadish, Ramakrishna Suresh, Nam Kihoon, Seon Choi Chang, Kim Jongkil, Kim Sung Hwa, Cho Hyong Jin, Shin HeungSoo, Kim Hyongbum, Kim Sung Wan, Lee Sang-Kyung, Kumar Priti
Abstract excerpt
Stem cells are poorly permissive to non-viral gene transfection reagents. In this study, we explored the possibility of improving gene delivery into human embryonic (hESC) and mesenchymal (hMSC) stem cells by synergizing the activity of a cell-binding ligand with a polymer that releases nucleic a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
