Article

Lipid nanoparticle-mediated delivery of mRNA into the mouse and human retina and other ocular tissues

2023-07-13

Abstract excerpt

<h4>Structured Abstract</h4> <h4>Purpose</h4> Lipid nanoparticles (LNPs) show promise in their ability to introduce mRNA to drive protein expression in specific cell types of the mammalian eye. Here, we examined the ability of mRNA encapsulated in lipid nanoparticles (LNPs) with two distinct formulations to drive gene expression in mouse and human retina and other ocular tissues. <h4>Methods</h4> We introduced...

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Literature Corpus work: 0ed6a8c9-e95b-505a-a1fc-82b40fe869b8
DOI: 10.1101/2023.07.13.548758

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