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Article

Gene Delivery in the Cornea: In Vitro & Ex Vivo Evaluation of Solid Lipid Nanoparticle-Based Vectors

24 May 2018

Abstract excerpt

AIM: Inflammation is a process that underlies sight-threatening ocular surface diseases, and gene supplementation with the plasmid that encodes for p-IL10 will allow the sustained de novo synthesis of the cytokine to occur in corneal cells, and provide a long-term anti-inflammatory effect. This work describes the development of solid lipid nanoparticle systems for the delivery of p-IL10 to transfect the cornea....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29792369
DOI: 10.2217/nnm-2018-0112

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